![]() He characterized metabolism, localisation and functions of histamine, dopamine and their receptors. The Science paper with Monique Garbarg as first author (1974) predicted the approximate location of the histamine system, 10 years before it became visible through the work of Hiroshi Wada, Takehiko Watanabe and Pertti Panula. histamine formation in rat brain 1971, the fall of brain histamine under hypnotics and the cyclic AMP signaling in 1975. He published many seminal papers in leading journals that founded the recognition of histamine as an important transmitter, e.g. He was professor of physiology at both pharmacy faculties of the universities Haute Normandie (Rouen) and Paris 5, and head of the INSERM unit “Neurobiology and Pharmacology” from 1972 – 2001. He published his first paper on histamine in 1962 – in the kidney, in 1969 he went to the stomach where he predicted the usefulness of removing the HA action on acid secretion. With all these influences and so much more bleeding into the current Dusky studio alchemies, the journey is just beginning for the London duo.Jean-Charles Schwartz, born 1936, has made major contributions to neuroscience, the understanding of neurotransmitters, especially histamine, dopamine, serotonin and neuropeptides as well as the pharmacological treatment of neuropsychiatric diseases. Sift through Nick and Alfie's personal record collections and you will find everything from Polish orchestral music and Ahmad Jamal's soulful jazz, to Justin Martin's "Sad Piano" and Daft Punk's formative French house, with stacks of vintage garage and drum & bass 12"s propping the whole selection up. The eclectic, well-honed outlook is the result of absorbing two decades of global dance music, digging back beyond and a shared production career that has spanned nearly 10 years. Now with the launch of their 17 Steps label, the duo are taking control of this unique identity and giving it the unrestricted platform it deserves. A stamp of quality, that makes for an instantly recognisable 'Dusky' sound. But whatever musical sub-strain Dusky turn their hands to, there is always a strong common thread - a signature depth and detailing. There have been rugged warehouse techno excursions on Loefah's School, quirky scene-defining house bangers on Aus and classy melodic grooves like 'Mr Man' on Anjunadeep. Since those formative releases marked them out as talents destined for the top, Dusky have pushed their sound forward every step of the way - refusing to stay stationary and acknowledge the status quo. An underground anthem that crossed over many barriers, it eventually earned the unexpected accolade of iTunes Dance Single Of The Year. Signed by the label that broke Maya Jane Coles (Dogmatik), its devastating deep grooves were hammered by everyone from Loefah, Joy Orbison and Boddika to Disclosure, Jamie Jones and Sasha, with even Calvin Harris getting in on the act. The Dusky story began back in 2011, with the birth of their new alias on the beautifully diverse 'Stick By This' LP - an album that quickly found a vocal champion in Radio 1's Pete Tong.īut the duo's breakthrough track was undoubtedly 2012's killer 'Flo Jam'. BBC Essential Mix of the Year contenders, DJ Magazine cover stars, headliners everywhere from Berlin's Panorama Bar to London's Fabric, Dusky's story so far is one of constant forward motion and a uniquely universal appeal. ![]() In just three years, the fast-rising duo have asserted themselves as leaders of the UK underground. If you or a friend feels uncomfortable, please let a Flash team member know ~ our staff is trained to take action and assist.Īnd always remember, no photos/videos on the dance floors for the sake of the vibe! ❤️ĭusky are London production duo Nick Harriman and Alfie Granger-Howell. Dusky have established themselves as premier acts of the UK underground scene.įlash stands firmly against non-consensual behavior, discrimination, harassment or harm of any kind. The duo’s releases on Gerd Janson’s Running Back label and their own 17 Steps imprint have received support across BBC Radio 1, Resident Advisor and Mixmag. Initially gaining recognition during the UK’s 2011 house renaissance, Dusky have since established a diverse and unique sound that draws on everything from Detroit techno to ambient, progressive house, jazz, and experimental sounds. ![]() Get notified about future events by texting “FLASH" to (855) 957-2349ĭUSKY’s string of recent singles and outstanding 2021 album JOY have taken the duo to another level, thanks to some of their best material to date. Advance Tickets on sale Friday, April 22nd.
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